参考文献

［1］SHETELIG C，LIMALANATHAN S，HOFFMANN P，et al.Association of IL-8 With infarct size and clinical outcomes in patients with STEMI.J Am Coll Cardiol，2018，72（2）：187-198.

［2］LECHNER J，CHEN M，HOGG R E，et al.Peripheral blood mononuclear cells from neovascular agerelated macular degeneration patients produce higher levels of chemokines CCL2（MCP-1）and CXCL8（IL-8）.J Neuroinflammation，2017，14（1）：42.

［3］JAERVE A，MÜLLER H W.Chemokines in CNS injury and repair.Cell Tissue Res，2012，349（1）：229-248.

［4］ADLER M W，ROGERS T J.Are chemokines the third major system in the brain？J Leukoc Biol，2005，78（6）：1204-1209.

［5］ROSTÈNE W，KITABGI P，PARSADANIANTZ S M.Chemokines：a new class of neuromodulator？Nat Rev Neurosci，2007，8（11）：895-903.

［6］ZHANG Z J，JIANG B C，GAO Y J，Chemokines in neuron-glial cell interaction and pathogenesis of neuropathic pain.Cell Mol Life Sci，2017，74（18）：3275-3291.

［7］ZHU B，GONG Y，SHEN L，et al.Total Panax notoginseng saponin inhibits vascular smooth muscle cell proliferation and migration and intimal hyperplasia by regulating WTAP/p16 signals via m6A modulation.Biomed Pharmacother，2020，124：109935.

［8］THULASITHA W S，UMASUTHAN N，WHANG I，et al.A CXC chemokine gene，CXCL12，from rock bream，oplegnathus fasciatus：molecular characterization and transcriptional profile.Fish Shellfish Immunol，2015，45（2）：560-566.

［9］SUZUKI M，EL-HAGE N，ZOU S，et al.Fractalkine/CX3CL1 protects striatal neurons from synergistic morphine and HIV-1 Tat-induced dendritic losses and death.Mol Neurodegener，2011，6：78.

［10］MAMIK M K，GHORPADE A.CXCL8 as a potential therapeutic target for HIV-associated neurocognitive disorders.Curr Drug Targets，2016，17（1）：111-121.

［11］OZAWA P M，ARIZA C B，ISHIBASHI C M，et al.Role of CXCL12 and CXCR4 in normal cerebellar development and medulloblastoma.Int J Cancer，2016，138（1）：10-13.

［12］ADLER M W，GELLER E B，CHEN X，et al.Viewing chemokines as a third major system of communication in the brain.AAPS J，2006，7（4）：E865-E870.

［13］SHERIDAN G K，MURPHY K J.Neuron-glia crosstalk in health and disease：fractalkine and CX3CR1 take centre stage.Open Biol，2013，3（12）：130181.

［14］BASILICO B，PAGANI F，GRIMALDI A，et al.Microglia shape presynaptic properties at developing glutamatergic synapses.Glia，2019，67（1）：53-67.

［15］JOBLING A I，WAUGH M，VESSEY K A，et al.The role of the microglial CX3CR1 pathway in the postnatal maturation of retinal photoreceptors.J Neurosci，2018，38（20）：4708-4723.

［16］CONDUCTIER G，BLONDEAU N，GUYON A，et al.The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases.J Neuroimmunol，2010，224（1/2）：93-100.

［17］PADOVANI-CLAUDIO D A，LIU L，RANSOHOFF R M，et al.Alterations in the oligodendrocyte lineage，myelin，and white matter in adult mice lacking the chemokine receptor CXCR2.Glia，2006，54（5）：471-483.

［18］COUGHLAN C M，MCMANUS C M，SHARRON M，et al.Expression of multiple functional chemokine receptors and monocyte chemoattractant protein-1 in human neurons.Neuroscience，2000，97（3）：591-600.

［19］LINNE M L，JALONEN T O.Astrocyte-neuron interactions：from experimental research-based models to translational medicine.Prog Mol Biol Transl Sci，2014，123：191-217.

［20］NAKAGAWA S，IZUMI Y，TAKADA-TAKATORI Y，et al.Increased CCL6 expression in astrocytes and neuronal protection from neuron-astrocyte interactions.Biochem Biophys Res Commun，2019，519（4）：777-782.

［21］PARK M H，LEE Y K，LEE Y H，et al.Chemokines released from astrocytes promote chemokine receptor 5-mediated neuronal cell differentiation.Exp Cell Res，2009，315（16）：2715-2726.

［22］MARTIN J E，NGUYEN T T，GRUNSEICH C，et al.Decreased motor neuron support by SMA astrocytes due to diminished MCP1 Secretion.J Neurosci，2017，37（21）：5309-5318.

［23］NI H，WANG Y，AN K，et al.Crosstalk between NFκB-dependent astrocytic CXCL1 and neuron CXCR2 plays a role in descending pain facilitation.J Neuroinflammation，2019，16（1）：1.

［24］SHEN W，HU X M，LIU Y N，et al.CXCL12 in astrocytes contributes to bone cancer pain through CXCR4-mediated neuronal sensitization and glial activation in rat spinal cord.J Neuroinflammation，2014，11：75.

［25］KE B C，HUANG X X，LI Y，et al.Neuronal-derived CCL7 drives neuropathic pain by promoting astrocyte proliferation.Neuroreport，2016，27（11）：849-857.

［26］PAOLICELLI R C，BOLASCO G，PAGANI F，et al.Synaptic pruning by microglia is necessary for normal brain development.Science，2011，333（6048）：1456-1458.

［27］LUO P，CHU S F，ZHANG Z，et al.Fractalkine/CX3CR1 is involved in the cross-talk between neuron and glia in neurological diseases.Brain Res Bull，2019，146：12-21.

［28］ANASTASSIA V，SCOTT A Y，BEARTRIX S W，et al.Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain.Neuron，2017，94（3）：500-516.

［29］HAWRA K，SUNG H K，ANDREW S L，et al.Increase in chemokine CXCL1 by ERβ ligand treatment is a key mediator in promoting axon myelination.Proc Natl Acad Sci U S A，2018，115（24）：6291-6296.

［30］HUI H T，JIANGIN N，ROEBEN M，et al.Oligodendrocyte precursors migrate along vasculature in the developing nervous system.Science，2016，351（6271）：379-384.